PHD POSITION

PhD Studentship: Uncovering the mechanism of minor spliceosome autoimmune diabetes

Deadline: 5 Jan 2027 · 54 days left

Institution: University of Exeter
Country: United Kingdom
Field: Life sciences and medicine
Type: PhD position
Pay: The studentship funding is for Home tuition fees, as well as a Doctoral Stipend for up to 4 years.
Deadline: 5 Jan 2027 · 54 days left

About this position

Context/background Before the instructions in a gene can be used, non-coding parts called introns must be cut out in a process called splicing. Most introns are spliced out by the major spliceosome. However, around 700 human genes contain a rare type of intron (U12 introns) that can only be removed by a separate minor spliceosome. We recently discovered that inherited changes in two core minor spliceosome components, RNU4ATAC and RNU6ATAC, cause a single-gene (monogenic) form of autoimmune diabetes. In this condition, the immune system destroys the insulin-producing beta cells of the pancreas.

Who can apply

Nationality and visa rules

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Deadlines and how to apply

Applications close on 5 Jan 2027 (54 days from today). Apply on the official page; PhD Atlas does not collect applications.

Read the official call and apply

Official call: https://www.jobs.ac.uk/job/DTL149/phd-studentship-uncovering-the-mechanism-of-minor-spliceosome-autoimmune-diabetes

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